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The preclinical work done with the GLP-1s shows that they seem to affect the areas in the brain that are involved in reward, he explained

In some cases, especially at the beginning of treatment for a severe deficiency, injections might be given more frequently (e.g., daily or every other day) for a short period before transitioning to a maintenance schedule

However, the study team was not able to draw any causal links between the initiation of these therapies and onset of ophthalmic conditions reported but said they could be the effect of rapid hyperglycemia corrections

Study of insulin resistance in relation to serum IGF-I levels in subjects with different degrees of glucose tolerance

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